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Glyceraldehyde 3-phosphate dehydrogenase-S, a sperm-specific glycolytic enzyme, is required for sperm motility and male fertility

Although glycolysis is highly conserved, it is remarkable that several unique isozymes in this central metabolic pathway are found in mammalian sperm. Glyceraldehyde 3-phosphate dehydrogenase-S (GAPDS) is the product of a mouse gene expressed only during spermatogenesis and, like its human ortholog...

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Detalhes bibliográficos
Main Authors: Miki, Kiyoshi, Qu, Weidong, Goulding, Eugenia H., Willis, William D., Bunch, Donna O., Strader, Lillian F., Perreault, Sally D., Eddy, Edward M., O'Brien, Deborah A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC534542/
https://ncbi.nlm.nih.gov/pubmed/15546993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407708101
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