Recombinant human sperm-specific glyceraldehyde-3-phosphate dehydrogenase (GAPDHS) is expressed at high yield as an active homotetramer in baculovirus-infected insect cells

The sperm-specific glyceraldehyde-3-phosphate dehydrogenase (GAPDHS) isoform is a promising contraceptive target because it is specific to male germ cells, essential for sperm motility and male fertility, and well suited to pharmacological inhibition. However, GAPDHS is difficult to isolate from nat...

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Detaylı Bibliyografya
Asıl Yazarlar: Lamson, David R., House, Alan J., Danshina, Polina V., Sexton, Jonathan Z., Sanyang, Khaddijatou, O’Brien, Deborah A., Yeh, Li-An, Williams, Kevin P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992962/
https://ncbi.nlm.nih.gov/pubmed/20828617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pep.2010.09.003
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