Recombinant human sperm-specific glyceraldehyde-3-phosphate dehydrogenase (GAPDHS) is expressed at high yield as an active homotetramer in baculovirus-infected insect cells

The sperm-specific glyceraldehyde-3-phosphate dehydrogenase (GAPDHS) isoform is a promising contraceptive target because it is specific to male germ cells, essential for sperm motility and male fertility, and well suited to pharmacological inhibition. However, GAPDHS is difficult to isolate from nat...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Lamson, David R., House, Alan J., Danshina, Polina V., Sexton, Jonathan Z., Sanyang, Khaddijatou, O’Brien, Deborah A., Yeh, Li-An, Williams, Kevin P.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992962/
https://ncbi.nlm.nih.gov/pubmed/20828617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pep.2010.09.003
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares