Development and Implementation of a High Throughput Screen for the Human Sperm-Specific Isoform of Glyceraldehyde 3-Phosphate Dehydrogenase (GAPDHS)

Glycolytic isozymes that are restricted to the male germline are potential targets for the development of reversible, non-hormonal male contraceptives. GAPDHS, the sperm-specific isoform of glyceraldehyde-3-phosphate dehydrogenase, is an essential enzyme for glycolysis making it an attractive target...

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Main Authors: Sexton, Jonathan Z, Danshina, Polina V, Lamson, David R, Hughes, Mark, House, Alan J, Yeh, Li-An, O’Brien, Deborah A, Williams, Kevin P
Format: Artigo
Jezik:Inglês
Izdano: Bentham Open 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134944/
https://ncbi.nlm.nih.gov/pubmed/21760877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1875397301105010030
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