Mitochondrial biogenesis by NO yields functionally active mitochondria in mammals

We recently found that long-term exposure to nitric oxide (NO) triggers mitochondrial biogenesis in mammalian cells and tissues by activation of guanylate cyclase and generation of cGMP. Here, we report that the NO/cGMP-dependent mitochondrial biogenesis is associated with enhanced coupled respirati...

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Autors principals: Nisoli, Enzo, Falcone, Sestina, Tonello, Cristina, Cozzi, Valeria, Palomba, Letizia, Fiorani, Mara, Pisconti, Addolorata, Brunelli, Silvia, Cardile, Annalisa, Francolini, Maura, Cantoni, Orazio, Carruba, Michele O., Moncada, Salvador, Clementi, Emilio
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC534517/
https://ncbi.nlm.nih.gov/pubmed/15545607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405432101
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