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TNF-α downregulates eNOS expression and mitochondrial biogenesis in fat and muscle of obese rodents
Obesity is associated with chronic low-grade inflammation. Thus, at metabolically relevant sites, including adipose tissue and muscle, there is abnormal production of proinflammatory cytokines such as TNF-α. Here we demonstrate that eNOS expression was reduced, with a concomitant reduction of mitoch...
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| 主要な著者: | , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
2006
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1564431/ https://ncbi.nlm.nih.gov/pubmed/16981010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI28570 |
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