A Gα12-specific Binding Domain in AKAP-Lbc and p114RhoGEF

AKAP-Lbc is a Rho-activating guanine nucleotide exchange factor (RhoGEF) important in heart development and pro-fibrotic signaling in cardiomyocytes. Heterotrimeric G proteins of the G12/13 subfamily, comprising Gα12 and Gα13, are well characterized as stimulating a specialized group of RhoGEFs thro...

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Vydáno v:J Mol Signal
Hlavní autoři: Martin, Joseph W., Cavagnini, Kyle S., Brawley, Douglas N., Berkley, Carrie Y., Smolski, William C., Garcia, Ricardo D., Towne, Autumn L., Sims, Jonathan R., Meigs, Thomas E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Ubiquity Press 2016
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345129/
https://ncbi.nlm.nih.gov/pubmed/31051012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5334/1750-2187-11-3
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