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A Gα12-specific Binding Domain in AKAP-Lbc and p114RhoGEF
AKAP-Lbc is a Rho-activating guanine nucleotide exchange factor (RhoGEF) important in heart development and pro-fibrotic signaling in cardiomyocytes. Heterotrimeric G proteins of the G12/13 subfamily, comprising Gα12 and Gα13, are well characterized as stimulating a specialized group of RhoGEFs thro...
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| Publié dans: | J Mol Signal |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Ubiquity Press
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5345129/ https://ncbi.nlm.nih.gov/pubmed/31051012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5334/1750-2187-11-3 |
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