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Genetic interactions and functional analyses of the fission yeast gsk3 and amk2 single and double mutants defective in TORC1-dependent processes

The Target of Rapamycin (TOR) signalling network plays important roles in aging and disease. The AMP-activated protein kinase (AMPK) and the Gsk3 kinase inhibit TOR during stress. We performed genetic interaction screens using synthetic genetic arrays (SGA) with gsk3 and amk2 as query mutants, the l...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Rallis, Charalampos, Townsend, StJohn, Bähler, Jürg
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345095/
https://ncbi.nlm.nih.gov/pubmed/28281664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44257
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