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Recruitment of IκBα to the hes1 promoter is associated with transcriptional repression

The NF-κB pathway plays a pivotal role in proliferation, differentiation, apoptosis, and immune responses in mammals. The NF-κB inhibitor, IκB, has classically been characterized for its ability to sequester NF-κB transcription factors in the cytoplasm. Nevertheless, a nuclear fraction of IκBα has c...

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Autori principali: Aguilera, Cristina, Hoya-Arias, Ruben, Haegeman, Guy, Espinosa, Lluís, Bigas, Anna
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC534509/
https://ncbi.nlm.nih.gov/pubmed/15536134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404429101
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