Hes6 Promotes Cortical Neurogenesis and Inhibits Hes1 Transcription Repression Activity by Multiple Mechanisms

Hes1 is a mammalian basic helix-loop-helix transcriptional repressor that inhibits neuronal differentiation together with corepressors of the Groucho (Gro)/Transducin-like Enhancer of split (TLE) family. The interaction of Hes1 with Gro/TLE is mediated by a WRPW tetrapeptide present in all Hairy/Enh...

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Bibliographic Details
Main Authors: Gratton, Michel-Olivier, Torban, Elena, Jasmin, Stephanie Belanger, Theriault, Francesca M., German, Michael S., Stifani, Stefano
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC193938/
https://ncbi.nlm.nih.gov/pubmed/12972610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.19.6922-6935.2003
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