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NF-κB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation

Cells latently infected with HIV represent a currently insurmountable barrier to viral eradication in infected patients. Using the J-Lat human T-cell model of HIV latency, we have investigated the role of host factor binding to the κB enhancer elements of the HIV long terminal repeat (LTR) in the ma...

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Bibliografske podrobnosti
Main Authors: Williams, Samuel A, Chen, Lin-Feng, Kwon, Hakju, Ruiz-Jarabo, Carmen M, Verdin, Eric, Greene, Warner C
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1356344/
https://ncbi.nlm.nih.gov/pubmed/16319923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600900
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