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Cotranslational dimerization of the Rel homology domain of NF-κB1 generates p50–p105 heterodimers and is required for effective p50 production
Generation of the NF-κB p50 transcription factor is mediated by the proteasome. We found previously that p50 is generated during translation of the NFKB1 gene and that this cotranslational processing allows the production of both p50 and p105 from a single mRNA. We now demonstrate that the Rel homol...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC302078/ https://ncbi.nlm.nih.gov/pubmed/10970863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.17.4712 |
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