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Fluorescent indicators of cAMP and Epac activation reveal differential dynamics of cAMP signaling within discrete subcellular compartments

Second messenger cAMP regulates many cellular functions through its effectors, such as cAMP-dependent protein kinase (PKA) and Epac (exchange proteins directly activated by cAMP). Spatial and temporal control of cAMP signaling is crucial to differential regulation of cellular targets involved in var...

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Detalhes bibliográficos
Main Authors: DiPilato, Lisa M., Cheng, Xiaodong, Zhang, Jin
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC534508/
https://ncbi.nlm.nih.gov/pubmed/15545605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405973101
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