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Fluorescent indicators of cAMP and Epac activation reveal differential dynamics of cAMP signaling within discrete subcellular compartments

Second messenger cAMP regulates many cellular functions through its effectors, such as cAMP-dependent protein kinase (PKA) and Epac (exchange proteins directly activated by cAMP). Spatial and temporal control of cAMP signaling is crucial to differential regulation of cellular targets involved in var...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: DiPilato, Lisa M., Cheng, Xiaodong, Zhang, Jin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2004
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC534508/
https://ncbi.nlm.nih.gov/pubmed/15545605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405973101
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