BACE1 across species: a comparison of the in vivo consequences of BACE1 deletion in mice and rats

Assessing BACE1 (β-site APP cleaving enzyme 1) knockout mice for general health and neurological function may be useful in predicting risks associated with prolonged pharmacological BACE1 inhibition, a treatment approach currently being developed for Alzheimer’s disease. To determine whether BACE1 d...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Weber, Martin, Wu, Tiffany, Meilandt, William J., Dominguez, Sara L., Solanoy, Hilda O., Maloney, Janice A., Ngu, Hai, Baca, Miriam, Kung, Chung, Lima, Lisa, Earr, Timothy K., Fleck, Daniel, Shields, Shannon D., Forrest, William F., Foreman, Oded, Warming, Søren, Watts, Ryan J., Scearce-Levie, Kimberly
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345047/
https://ncbi.nlm.nih.gov/pubmed/28281673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44249
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados