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BACE1 across species: a comparison of the in vivo consequences of BACE1 deletion in mice and rats
Assessing BACE1 (β-site APP cleaving enzyme 1) knockout mice for general health and neurological function may be useful in predicting risks associated with prolonged pharmacological BACE1 inhibition, a treatment approach currently being developed for Alzheimer’s disease. To determine whether BACE1 d...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5345047/ https://ncbi.nlm.nih.gov/pubmed/28281673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44249 |
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