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APP Function and Lipids: A Bidirectional Link

Extracellular neuritic plaques, composed of aggregated amyloid-β (Aβ) peptides, are one of the major histopathological hallmarks of Alzheimer’s disease (AD), a progressive, irreversible neurodegenerative disorder and the most common cause of dementia in the elderly. One of the most prominent risk fa...

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Detalles Bibliográficos
Publicado en:Front Mol Neurosci
Main Authors: Grimm, Marcus O. W., Mett, Janine, Grimm, Heike S., Hartmann, Tobias
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5344993/
https://ncbi.nlm.nih.gov/pubmed/28344547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00063
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