Plasmalogens Inhibit APP Processing by Directly Affecting γ-Secretase Activity in Alzheimer's Disease

Lipids play an important role as risk or protective factors in Alzheimer's disease (AD). Previously it has been shown that plasmalogens, the major brain phospholipids, are altered in AD. However, it remained unclear whether plasmalogens themselves are able to modulate amyloid precursor protein...

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Detalhes bibliográficos
Main Authors: Rothhaar, Tatjana L., Grösgen, Sven, Haupenthal, Viola J., Burg, Verena K., Hundsdörfer, Benjamin, Mett, Janine, Riemenschneider, Matthias, Grimm, Heike S., Hartmann, Tobias, Grimm, Marcus O. W.
Formato: Artigo
Idioma:Inglês
Publicado em: The Scientific World Journal 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322458/
https://ncbi.nlm.nih.gov/pubmed/22547976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1100/2012/141240
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