Intracellular APP Domain Regulates Serine-Palmitoyl-CoA Transferase Expression and Is Affected in Alzheimer's Disease

Lipids play an important role as risk or protective factors in Alzheimer's disease (AD), a disease biochemically characterized by the accumulation of amyloid beta peptides (Aβ), released by proteolytic processing of the amyloid precursor protein (APP). Changes in sphingolipid metabolism have be...

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Detalhes bibliográficos
Main Authors: Grimm, Marcus O. W., Grösgen, Sven, Rothhaar, Tatjana L., Burg, Verena K., Hundsdörfer, Benjamin, Haupenthal, Viola J., Friess, Petra, Müller, Ulrike, Fassbender, Klaus, Riemenschneider, Matthias, Grimm, Heike S., Hartmann, Tobias
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE-Hindawi Access to Research 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109855/
https://ncbi.nlm.nih.gov/pubmed/21660213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/695413
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