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(13)C and (15)N Chemical Shift Assignments of Mammalian Y145Stop Prion Protein Amyloid Fibrils

The Y145Stop prion protein (PrP23–144), which has been linked to the development of a heritable prionopathy in humans, is a valuable in vitro model for elucidating the structural and molecular basis of amyloid seeding specificities. Here we report the sequential backbone and side-chain (13)C and (15...

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Detalhes bibliográficos
Publicado no:Biomol NMR Assign
Main Authors: Theint, Theint, Nadaud, Philippe S., Surewicz, Krystyna, Surewicz, Witold K., Jaroniec, Christopher P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5344711/
https://ncbi.nlm.nih.gov/pubmed/28004358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12104-016-9723-6
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