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Anti-trypanosomal activity of non-peptidic nitrile-based cysteine protease inhibitors
The cysteine protease cruzipain is considered to be a validated target for therapeutic intervention in the treatment of Chagas disease. Anti-trypanosomal activity against the CL Brener strain of T. cruzi was observed in the 0.1 μM to 1 μM range for three nitrile-based cysteine protease inhibitors ba...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | PLoS Negl Trop Dis |
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| Κύριοι συγγραφείς: | , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Public Library of Science
2017
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5344518/ https://ncbi.nlm.nih.gov/pubmed/28222138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005343 |
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