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MC-PPEA as a new and more potent inhibitor of CLP-induced sepsis and pulmonary inflammation than FK866

Our previous study indicated that overexpression of nicotinamide phosphoribosyltransferase (NAMPT) aggravated acute lung injury, while knockdown of NAMPT expression attenuated ventilator-induced lung injury. Recently, we found that meta-carborane-butyl-3-(3-pyridinyl)-2E-propenamide (MC-PPEA, MC4),...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Drug Des Devel Ther
मुख्य लेखकों: Huang, Peixin, Lee, Mark W, Sadrerafi, Keivan, Heruth, Daniel P, Zhang, Li Q, Maulik, Dev, Ye, Shui Qing
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Dove Medical Press 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5344436/
https://ncbi.nlm.nih.gov/pubmed/28424540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S125349
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