Clickable prodrugs bearing potent and hydrolytically cleavable nicotinamide phosphoribosyltransferase inhibitors

di Sadrerafi, Keivan, Mason, Emilia O, Lee, Mark W
Pubblicato in Drug Des Devel Ther (2018)

MC-PPEA as a new and more potent inhibitor of CLP-induced sepsis and pulmonary inflammation than FK866

di Huang, Peixin, Lee, Mark W, Sadrerafi, Keivan, Heruth, Daniel P, Zhang, Li Q, Maulik, Dev, Ye, Shui Qing
Pubblicato in Drug Des Devel Ther (2017)

Rescue bisphosphonate treatment of alveolar bone improves extraction socket healing and reduces osteonecrosis in zoledronate-treated mice

di Hokugo, Akishige, Kanayama, Keiichi, Sun, Shuting, Morinaga, Kenzo, Sun, Yujie, Wu, QingQing, Sasaki, Hodaka, Okawa, Hiroko, Evans, Courtney, Ebetino, Frank H., Lundy, Mark W., Sadrerafi, Keivan, McKenna, Charles E., Nishimura, Ichiro
Pubblicato in Bone (2019)

Design, Synthesis, and Antimicrobial Evaluation of a Novel Bone-Targeting Bisphosphonate-Ciprofloxacin Conjugate for the Treatment of Osteomyelitis Biofilms

di Sedghizadeh, Parish P., Sun, Shuting, Junka, Adam F., Richard, Eric, Sadrerafi, Keivan, Mahabady, Susan, Bakhshalian, Neema, Tjokro, Natalia, Bartoszewicz, Marzenna, Oleksy, Monika, Szymczyk, Patrycja, Lundy, Mark W., Neighbors, Jeffrey D., Russell, R. Graham G., McKenna, Charles E., Ebetino, Frank H.
Pubblicato in J Med Chem (2017)