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Role of HGF–MET Signaling in Primary and Acquired Resistance to Targeted Therapies in Cancer
The Hepatocyte growth factor (HGF)—mesenchymal-epithelial transition (MET) pathway is deregulated in several cancers and is associated with aggressive phenotype and worse prognosis. MET, a tyrosine kinase receptor activated by HGF, plays a physiological role in embryogenesis, promoting cell growth,...
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| Veröffentlicht in: | Biomedicines |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5344276/ https://ncbi.nlm.nih.gov/pubmed/28548075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines2040345 |
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