Characterisation of mice lacking all functional isoforms of the pro-survival BCL-2 family member A1 reveals minor defects in the haematopoietic compartment

The pro-survival proteins of the BCL-2 family regulate the survival of all cells, and genetic deletion models for these proteins have revealed which specific BCL-2 family member(s) is/are critical for the survival of particular cell types. A1 is a pro-survival BCL-2-like protein that is expressed pr...

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Bibliographic Details
Published in:Cell Death Differ
Main Authors: Schenk, Robyn L, Tuzlak, Selma, Carrington, Emma M, Zhan, Yifan, Heinzel, Susanne, Teh, Charis E, Gray, Daniel H, Tai, Lin, Lew, Andrew M, Villunger, Andreas, Strasser, Andreas, Herold, Marco J
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5344213/
https://ncbi.nlm.nih.gov/pubmed/28085150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.156
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