The BCL-2 pro-survival protein A1 is dispensable for T cell homeostasis on viral infection

The physiological role of the pro-survival BCL-2 family member A1 has been debated for a long time. Strong mRNA induction in T cells on T cell receptor (TCR)-engagement suggested a major role of A1 in the survival of activated T cells. However, the investigation of the physiological roles of A1 was...

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Bibliographic Details
Published in:Cell Death Differ
Main Authors: Tuzlak, Selma, Schenk, Robyn L, Vasanthakumar, Ajithkumar, Preston, Simon P, Haschka, Manuel D, Zotos, Dimitra, Kallies, Axel, Strasser, Andreas, Villunger, Andreas, Herold, Marco J
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Original Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5344212/
https://ncbi.nlm.nih.gov/pubmed/28085151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.155
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