Overexpression of Mcl-1 exacerbates lymphocyte accumulation and autoimmune kidney disease in lpr mice

Cell death by apoptosis has a critical role during embryonic development and in maintaining tissue homeostasis. In mammals, there are two converging apoptosis pathways: the ‘extrinsic' pathway, which is triggered by engagement of cell surface ‘death receptors' such as Fas/APO-1; and the ‘i...

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Bibliographic Details
Published in:Cell Death Differ
Main Authors: Anstee, Natasha S, Vandenberg, Cassandra J, Campbell, Kirsteen J, Hughes, Peter D, O'Reilly, Lorraine A, Cory, Suzanne
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Original Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5344201/
https://ncbi.nlm.nih.gov/pubmed/27813531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.125
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