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Absence of CD59 exacerbates systemic autoimmunity in MRL/lpr mice()

CD59 is a glycosylphosphatidylinositol (GPI)-anchored membrane regulator of complement expressed on blood cells as well as peripheral tissues. It protects host cells from complement injury by inhibiting formation of the membrane attack complex. Recent studies in mice have suggested also a role of CD...

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Detalhes bibliográficos
Main Authors: Miwa, Takashi, Zhou, Lin, Maldonado, Michael A., Madaio, Michael P, Eisenberg, Robert A., Song, Wen-Chao
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3507618/
https://ncbi.nlm.nih.gov/pubmed/23109726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201621
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