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Decay-Accelerating Factor Ameliorates Systemic Autoimmune Disease in MRL/lpr Mice via Both Complement-Dependent and -Independent Mechanisms

Decay-accelerating factor (DAF) is a glycosylphosphatidylinositol-anchored membrane protein that restricts complement activation on autologous cells. Previous studies have established a significant protective activity of DAF in the MRL/lpr murine model of human systemic lupus erythematosus. To disse...

詳細記述

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書誌詳細
主要な著者: Miwa, Takashi, Maldonado, Michael A., Zhou, Lin, Yamada, Koei, Gilkeson, Gary S., Eisenberg, Robert A., Song, Wen-Chao
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Investigative Pathology 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829459/
https://ncbi.nlm.nih.gov/pubmed/17392165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060601
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