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Crystal Structure of the Heterotrimeric Integrin-Binding Region of Laminin-111

Laminins are cell-adhesive glycoproteins that are essential for basement membrane assembly and function. Integrins are important laminin receptors, but their binding site on the heterotrimeric laminins is poorly defined structurally. We report the crystal structure at 2.13 Å resolution of a minimal...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Structure
Main Authors: Pulido, David, Hussain, Sadaf-Ahmahni, Hohenester, Erhard
Format: Artigo
Jezik:Inglês
Izdano: Cell Press 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5343747/
https://ncbi.nlm.nih.gov/pubmed/28132784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2017.01.002
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