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Crystal Structure of the LG1-3 Region of the Laminin α2 Chain

Laminins are large heterotrimeric glycoproteins with many essential functions in basement membrane assembly and function. Cell adhesion to laminins is mediated by a tandem of five laminin G-like (LG) domains at the C terminus of the α chain. Integrin binding requires an intact LG1-3 region, as well...

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Autori principali: Carafoli, Federico, Clout, Naomi J., Hohenester, Erhard
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755686/
https://ncbi.nlm.nih.gov/pubmed/19553699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.026658
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