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Crystal Structure of the Heterotrimeric Integrin-Binding Region of Laminin-111

Laminins are cell-adhesive glycoproteins that are essential for basement membrane assembly and function. Integrins are important laminin receptors, but their binding site on the heterotrimeric laminins is poorly defined structurally. We report the crystal structure at 2.13 Å resolution of a minimal...

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Detalhes bibliográficos
Publicado no:Structure
Main Authors: Pulido, David, Hussain, Sadaf-Ahmahni, Hohenester, Erhard
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5343747/
https://ncbi.nlm.nih.gov/pubmed/28132784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2017.01.002
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