Cargando...
Correlation of fitness landscapes from three orthologous TIM barrels originates from sequence and structure constraints
Sequence divergence of orthologous proteins enables adaptation to environmental stresses and promotes evolution of novel functions. Limits on evolution imposed by constraints on sequence and structure were explored using a model TIM barrel protein, indole-3-glycerol phosphate synthase (IGPS). Fitnes...
Gardado en:
| Publicado en: | Nat Commun |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2017
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5343507/ https://ncbi.nlm.nih.gov/pubmed/28262665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14614 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|