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Effects of C2ta genetic polymorphisms on MHC class II expression and autoimmune diseases
Antigen presentation by the MHC‐II to CD4(+) T cells is important in adaptive immune responses. The class II transactivator (CIITA in human and C2TA in mouse) is the master regulator of MHC‐II gene expression. It coordinates the transcription factors necessary for the transcription of MHC‐II molecul...
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| Pubblicato in: | Immunology |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5343355/ https://ncbi.nlm.nih.gov/pubmed/27861821 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12692 |
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