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Effects of C2ta genetic polymorphisms on MHC class II expression and autoimmune diseases

Antigen presentation by the MHC‐II to CD4(+) T cells is important in adaptive immune responses. The class II transactivator (CIITA in human and C2TA in mouse) is the master regulator of MHC‐II gene expression. It coordinates the transcription factors necessary for the transcription of MHC‐II molecul...

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Publicat a:Immunology
Autors principals: Yau, Anthony C. Y., Piehl, Fredrik, Olsson, Tomas, Holmdahl, Rikard
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5343355/
https://ncbi.nlm.nih.gov/pubmed/27861821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12692
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