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Effects of C2ta genetic polymorphisms on MHC class II expression and autoimmune diseases
Antigen presentation by the MHC‐II to CD4(+) T cells is important in adaptive immune responses. The class II transactivator (CIITA in human and C2TA in mouse) is the master regulator of MHC‐II gene expression. It coordinates the transcription factors necessary for the transcription of MHC‐II molecul...
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| Publicado no: | Immunology |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5343355/ https://ncbi.nlm.nih.gov/pubmed/27861821 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12692 |
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