Heat Shock Protein HSP27 Secretion by Ovarian Cancer Cells Is Linked to Intracellular Expression Levels, Occurs Independently of the Endoplasmic Reticulum Pathway and HSP27's Phosphorylation Status, and Is Mediated by Exosome Liberation

The heat shock protein HSP27 has been correlated in ovarian cancer (OC) patients with aggressiveness and chemoresistance and, therefore, represents a promising potential biomarker for OC diagnosis, prognosis, and treatment response. Notably, secretion of soluble HSP27 has been described by a few cel...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:Dis Markers
المؤلفون الرئيسيون: Stope, Matthias B., Klinkmann, Gerd, Diesing, Karoline, Koensgen, Dominique, Burchardt, Martin, Mustea, Alexander
التنسيق: Artigo
اللغة:Inglês
منشور في: Hindawi Publishing Corporation 2017
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC5343262/
https://ncbi.nlm.nih.gov/pubmed/28325957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/1575374
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