Heat Shock Protein HSP27 Secretion by Ovarian Cancer Cells Is Linked to Intracellular Expression Levels, Occurs Independently of the Endoplasmic Reticulum Pathway and HSP27's Phosphorylation Status, and Is Mediated by Exosome Liberation

The heat shock protein HSP27 has been correlated in ovarian cancer (OC) patients with aggressiveness and chemoresistance and, therefore, represents a promising potential biomarker for OC diagnosis, prognosis, and treatment response. Notably, secretion of soluble HSP27 has been described by a few cel...

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Dades bibliogràfiques
Publicat a:Dis Markers
Autors principals: Stope, Matthias B., Klinkmann, Gerd, Diesing, Karoline, Koensgen, Dominique, Burchardt, Martin, Mustea, Alexander
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5343262/
https://ncbi.nlm.nih.gov/pubmed/28325957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/1575374
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