Endoplasmic Reticulum Lumenal Indicators in Drosophila Reveal Effects of HSP-Related Mutations on Endoplasmic Reticulum Calcium Dynamics

Genes for endoplasmic reticulum (ER)-shaping proteins are among the most commonly mutated in hereditary spastic paraplegia (HSP). Mutation of these genes in model organisms can lead to disruption of the ER network. To investigate how the physiological roles of the ER might be affected by such disrup...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Oliva, Megan K., Pérez-Moreno, Juan José, O’Shaughnessy, Jillian, Wardill, Trevor J., O’Kane, Cahir J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7438849/
https://ncbi.nlm.nih.gov/pubmed/32903680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.00816
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