Endoplasmic Reticulum Lumenal Indicators in Drosophila Reveal Effects of HSP-Related Mutations on Endoplasmic Reticulum Calcium Dynamics

Genes for endoplasmic reticulum (ER)-shaping proteins are among the most commonly mutated in hereditary spastic paraplegia (HSP). Mutation of these genes in model organisms can lead to disruption of the ER network. To investigate how the physiological roles of the ER might be affected by such disrup...

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Publicat a:Front Neurosci
Autors principals: Oliva, Megan K., Pérez-Moreno, Juan José, O’Shaughnessy, Jillian, Wardill, Trevor J., O’Kane, Cahir J.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7438849/
https://ncbi.nlm.nih.gov/pubmed/32903680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.00816
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