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Cholera Toxin: An Intracellular Journey into the Cytosol by Way of the Endoplasmic Reticulum
Cholera toxin (CT), an AB(5)-subunit toxin, enters host cells by binding the ganglioside GM1 at the plasma membrane (PM) and travels retrograde through the trans-Golgi Network into the endoplasmic reticulum (ER). In the ER, a portion of CT, the enzymatic A1-chain, is unfolded by protein disulfide is...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Molecular Diversity Preservation International
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3153193/ https://ncbi.nlm.nih.gov/pubmed/22069586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins2030310 |
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