A signaling cascade including ARID1A, GADD45B and DUSP1 induces apoptosis and affects the cell cycle of germ cell cancers after romidepsin treatment

In Western countries, the incidence of testicular germ cell cancers (GCC) is steadily rising over the last decades. Mostly, men between 20 and 40 years of age are affected. In general, patients suffering from GCCs are treated by orchiectomy and radio- or chemotherapy. Due to resistance mechanisms, i...

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Vydáno v:Oncotarget
Hlavní autoři: Nettersheim, Daniel, Jostes, Sina, Fabry, Martin, Honecker, Friedemann, Schumacher, Valerie, Kirfel, Jutta, Kristiansen, Glen, Schorle, Hubert
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342713/
https://ncbi.nlm.nih.gov/pubmed/27572311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11647
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