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A small molecule inhibitor of PAI-1 protects against doxorubicin-induced cellular senescence
Doxorubicin, an anthracycline antibiotic, is a commonly used anticancer drug. In spite of its widespread usage, its therapeutic effect is limited by its cardiotoxicity. On the cellular level, Doxorubicin-induced cardiotoxicity manifests as stress induced premature senescence. Previously, we demonstr...
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| Publicado no: | Oncotarget |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5341920/ https://ncbi.nlm.nih.gov/pubmed/27736799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12494 |
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