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PAI-1 is a critical regulator of FGF23 homeostasis

Elevated levels of fibroblast growth factor 23 (FGF23), a bone-derived phosphaturic hormone, are associated with a number of pathologic conditions including chronic kidney disease, cardiac hypertrophy, and congestive heart failure. Currently, there are no specific treatments available to lower plasm...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Eren, Mesut, Place, Aaron T., Thomas, Paul M., Flevaris, Panagiotis, Miyata, Toshio, Vaughan, Douglas E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5597312/
https://ncbi.nlm.nih.gov/pubmed/28924605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1603259
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