Artesunate enhances the therapeutic response of glioma cells to temozolomide by inhibition of homologous recombination and senescence

Glioblastoma multiforme (GBM), a malignant brain tumor with a dismal prognosis, shows a high level of chemo- and radioresistance and, therefore, attempts to sensitize glioma cells are highly desired. Here, we addressed the question of whether artesunate (ART), a drug currently used in the treatment...

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Vydáno v:Oncotarget
Hlavní autoři: Berte, Nancy, Lokan, Stefanie, Eich, Marcus, Kim, Ella, Kaina, Bernd
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341871/
https://ncbi.nlm.nih.gov/pubmed/27626497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11972
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