PML/RARa inhibits PTEN expression in hematopoietic cells by competing with PU.1 transcriptional activity

Acute promyelocitic leukemia (APL) is characterized by the pathognomonic presence in leukemic blasts of the hybrid protein PML/RARA, that acts as a transcriptional repressor impairing the expression of genes that are critical to myeloid differentiation. Here, we show that primary blasts from APL pat...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Oncotarget
मुख्य लेखकों: Noguera, Nélida Inés, Piredda, Maria Liliana, Taulli, Riccardo, Catalano, Gianfranco, Angelini, Giulia, Gaur, Girish, Nervi, Clara, Voso, Maria Teresa, Lunardi, Andrea, Pandolfi, Pier Paolo, Lo-Coco, Francesco
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Impact Journals LLC 2016
विषय:
Priority Research Paper
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341808/
https://ncbi.nlm.nih.gov/pubmed/27626703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11964
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