PML/RARa Interferes with NRF2 Transcriptional Activity Increasing the Sensitivity to Ascorbate of Acute Promyelocytic Leukemia Cells

NRF2 (NF-E2 p45-related factor 2) orchestrates cellular adaptive responses to stress. Its quantity and subcellular location is controlled through a complex network and its activity increases during redox perturbation, inflammation, growth factor stimulation, and energy fluxes. Even before all-trans...

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Dettagli Bibliografici
Pubblicato in:Cancers (Basel)
Autori principali: Banella, Cristina, Catalano, Gianfranco, Travaglini, Serena, Divona, Mariadomenica, Masciarelli, Silvia, Guerrera, Gisella, Fazi, Francesco, Lo-Coco, Francesco, Voso, Maria Teresa, Noguera, Nelida Ines
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7016898/
https://ncbi.nlm.nih.gov/pubmed/31905996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12010095
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