High-dose ascorbate and arsenic trioxide selectively kill acute myeloid leukemia and acute promyelocytic leukemia blasts in vitro

The use of high-dose ascorbate (ASC) for the treatment of human cancer has been attempted several decades ago and has been recently revived by several in vitro and in vivo studies in solid tumors. We tested the cytotoxic effects of ASC, alone or in combination with arsenic trioxide (ATO) in acute my...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Noguera, Nélida I., Pelosi, Elvira, Angelini, Daniela F., Piredda, Maria Liliana, Guerrera, Gisella, Piras, Eleonora, Battistini, Luca, Massai, Lauretta, Berardi, Anna, Catalano, Gianfranco, Cicconi, Laura, Castelli, Germana, D’Angiò, Agnese, Pasquini, Luca, Graziani, Grazia, Fioritoni, Giuseppe, Voso, Maria Teresa, Mastrangelo, Domenico, Testa, Ugo, Lo-Coco, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464808/
https://ncbi.nlm.nih.gov/pubmed/28427227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15925
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