High-dose ascorbate and arsenic trioxide selectively kill acute myeloid leukemia and acute promyelocytic leukemia blasts in vitro

The use of high-dose ascorbate (ASC) for the treatment of human cancer has been attempted several decades ago and has been recently revived by several in vitro and in vivo studies in solid tumors. We tested the cytotoxic effects of ASC, alone or in combination with arsenic trioxide (ATO) in acute my...

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Wydane w:Oncotarget
Główni autorzy: Noguera, Nélida I., Pelosi, Elvira, Angelini, Daniela F., Piredda, Maria Liliana, Guerrera, Gisella, Piras, Eleonora, Battistini, Luca, Massai, Lauretta, Berardi, Anna, Catalano, Gianfranco, Cicconi, Laura, Castelli, Germana, D’Angiò, Agnese, Pasquini, Luca, Graziani, Grazia, Fioritoni, Giuseppe, Voso, Maria Teresa, Mastrangelo, Domenico, Testa, Ugo, Lo-Coco, Francesco
Format: Artigo
Język:Inglês
Wydane: Impact Journals LLC 2017
Hasła przedmiotowe:
Research Paper
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464808/
https://ncbi.nlm.nih.gov/pubmed/28427227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15925
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