TGFβ2 Induces the Formation of Cross-Linked Actin Networks (CLANs) in Human Trabecular Meshwork Cells Through the Smad and Non-Smad Dependent Pathways

PURPOSE: Increased intraocular pressure results from increased aqueous humor (AH) outflow resistance at the trabecular meshwork (TM) due to pathologic changes including the formation of cross-linked actin networks (CLANs). Transforming growth factor β2 (TGFβ2) is elevated in the AH and TM of primary...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Invest Ophthalmol Vis Sci
Egile Nagusiak: Montecchi-Palmer, Michela, Bermudez, Jaclyn Y., Webber, Hannah C., Patel, Gaurang C., Clark, Abbot F., Mao, Weiming
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Association for Research in Vision and Ophthalmology 2017
Gaiak:
Glaucoma
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341625/
https://ncbi.nlm.nih.gov/pubmed/28241317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-19672
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