HDAC Inhibitor-Mediated Epigenetic Regulation of Glaucoma-Associated TGFβ2 in the Trabecular Meshwork

PURPOSE: Elevated intraocular pressure (IOP) in primary open-angle glaucoma (POAG) results from glaucomatous damage to the trabecular meshwork (TM). The glaucoma-associated factor TGFβ2 is increased in aqueous humor and TM of POAG patients. We hypothesize that histone acetylation has a role in dysre...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Bermudez, Jaclyn Y., Webber, Hannah C., Patel, Gaurang C., Liu, Xiangyang, Cheng, Yi-Qiang, Clark, Abbot F., Mao, Weiming
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2016
Assuntos:
Glaucoma
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973502/
https://ncbi.nlm.nih.gov/pubmed/27403998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs16-19446
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados